Applied Sciences, Vol. 10, Pages 7166: Seebeck–Peltier Transition Approach to Oncogenesis

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Applied Sciences, Vol. 10, Pages 7166: Seebeck–Peltier Transition Approach to Oncogenesis

Applied Sciences doi: 10.3390/app10207166

Authors:
Umberto Lucia
Giulia Grisolia

In this paper, a non-equilibrium thermodynamic approach to cancer is developed. The thermo-electric effects in the cell membrane are analysed, in relation to the Seebeck-like and the Peltier-like effects. The role of the cell membrane electric potential is studied from a thermodynamic viewpoint, pointing out the relation between the proliferation rate and the membrane potential, the existence of a thermodynamic threshold for the mitotic activity, the relation between metastases and membrane potential and the comprehension of the role of ions fluxes in the cell behaviour.



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